SYNERGISTIC IN VITRO ACTIVITY AND MECHANISM OF KBN LOTION AND MICONAZOLE NITRATE AGAINST DRUG-RESISTANT CANDIDA ALBICANS BIOFILMS

Synergistic in vitro activity and mechanism of KBN lotion and miconazole nitrate against drug-resistant Candida albicans biofilms

BackgroundIn the face of increasing antifungal resistance among Candida albicans biofilms, this study explores the efficacy of a combined treatment using Kangbainian lotion (KBN) and miconazole nitrate (MN) to address this challenge.MethodsUsing UPLC-Q-TOF/MS Analysis for Identification of Active Compounds in KBN Lotion; FICI for synergy evaluation

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ECE2 is a prognostic biomarker associated with m6A modification and involved in immune infiltration of lung adenocarcinoma

BackgroundThe targeted therapy for lung cancer relies on prognostic genes and requires further research.No research has been conducted to determine the effect of endothelin-converting enzyme 2 (ECE2) in lung cancer.MethodsWe analyzed the expression of ECE2 in lung adenocarcinoma (LUAD) and normal adjacent tissues and its relationship with clinicopa

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